Genotyping by Sequencing is an emerging technology for cost effective variant discovery and genotyping. However, current analysis tools do not fulfill all experimental design and analysis needs.
GBSX is a package of tools to first aid in experimental design, including choice of enzymes and barcode design. Secondly, it provides a first analysis step to demultiplex samples using in-line barcodes, providing fastq files that can easily be plugged into existing variant analysis pipelines.
Citing GBSX
We ask that you cite this paper if you use GBSX in work that leads to publication.
Herten, Koen and Hestand, Matthew S. and Vermeesch, Joris R. and Van Houdt, Jeroen KJ (2015) GBSX: a toolkit for experimental design and demultiplexing genotyping by sequencing experiments BMC Bioinformatics 2015, 16:73 doi:10.1186/s12859-015-0514-3
Licence
All parts of this tool is licenced under GPLv3.
A copy of this licence is included under LICENSE on the Github page.
Contact
Genomics Core
Center for Human Genetics
UZ – KU Leuven
Herestraat 49 PO box 602
B-3000 Leuven, Belgium
Mail: koen.herten@kuleuven.be